REFLECTANCE-MODE PULSE OXIMETRY

尽管脉搏血氧仪在过去几年中得到了广泛的应用 在临床监护应用中，脉搏血氧仪的理论基础 人们对此仍然知之甚少。因此，仪器仪表的发展 依赖于经验知识的缓慢获取。最近， 临床医生已经表达了对开发一种 经皮血氧仪在反射模式下工作，而不是在 传输模式。这样的设备可以在世界上的许多地方使用 身体，并可在休克和其他情况下在 哪些外周血流量会受到影响。使用光子扩散模型， 我们已经研究了对组织血流量等重要指标的影响 反射式血氧计校准中的变量 各种传感器配置。明胶/牛奶组织的测量 幻影和皮肤可以与模型预测相媲美。我们现在是 构建用于测量的固态传感器样机 皮肤反射率。测量血氧饱和度的新方法 释放的强度将在低氧动物模型中进行测试。

Although pulse oximeters have been used extensively over the last few years in clinical monitoring applications, the theoretical basis of pulse oximetry is still poorly understood. As a result, the development of instrumentation has relied on the slow acquisition of empirical knowledge. Recently, clinicians have expressed interest in the possibility of developing a transcutaneous oximeter that operates in the reflection mode, rather than in the transmission mode. Such a device could be used at many sites on the body, and may enable monitoring during shock and other conditions during which peripheral blood flow is compromised. Using a photon-diffusion model, we have studied the effect of tissue blood volume and other important variables on the calibration of reflectance-mode oximeters employing a variety of sensor configurations. Measurements from gelatin/milk tissue phantoms and skin compare favorably with model predictions. We are now constructing prototype solid-state sensors which will - be used to measure skin reflectance. New methods for determining blood oxygen saturation from remitted intensities will be tested in hypoxic animal models.