IMAGING OF BIOLOGICAL TISSUES USING HIGH-FREQUENCY INTENSITY-MODULATED LIGHT

使用高频强度调制光对生物组织成像

• 批准号: 3852968
• 负责人: J M SCHMITT
• 金额: --
• 依托单位: NATIONAL CENTER FOR RESEARCH RESOURCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3852968
• 关键词: biomedical equipment development; imaging /visualization /scanning; infrared spectrometry; lasers; light scattering; method development; phase change; tissues

In this study, we are exploring imaging applications of high-frequency diffusing-wave spectrophotometry. A turbid medium is illuminated at one or more points on its surface with modulated light from a mode-locked laser. By measuring the phase shift and modulation depth of light re-emitted from the surface of the medium, we attempt to locate absorbers embedded in the medium. Preliminary results show that by taking advantage of the coherent properties of the propagation of diffusing waves in a homogeneous medium, detection of absorbers located deep (one or two centimeters) below the surface can be accomplished.

在这项研究中，我们正在探索高频率的成像应用， 扩散波分光光度法 一个混浊的介质在一个 或其表面上的多个点与来自锁模 激光器 通过测量光的相移和调制深度 从介质表面重新发射，我们试图找到吸收器 嵌入在介质中。 初步结果显示，通过采取 扩散传播的相干特性的优点 均匀介质中的波，位于深处的吸收体的检测（一个 或两厘米）。