REFLECTANCE-MODE PULSE OXIMETRY

尽管脉搏血氧仪在过去几年中得到了广泛的应用 在各大医院，脉搏血氧饱和度的理论基础仍然是 人们对此知之甚少。因此，仪器仪表的发展 依赖于经验知识的缓慢获取。最近， 临床医生已经表达了对开发一种 在反射模式下运行的经皮血氧计，而不是 在传输模式下。这样的设备可以在世界上的许多地方使用 身体，并可在休克和其他情况下在 哪些外周血流量会受到影响。 我们的努力一直集中在提高对 脉搏血氧仪。我们已经开发了皮肤的光子扩散模型来 研究组织血容量等重要变量对脑出血的影响。 透射式和反射式血氧计的校准。 对组织模型和完整皮肤进行了测量，以证实 模型的有效性。 在模型结果的指导下，我们构造了固态反射率 可以放置在额头、面部和胸部的传感器，以获得 测量动脉血氧饱和度。

Although pulse oximeters have been used extensively over the last few years in all major hospitals, the theoretical basis of pulse oximetry is still poorly understood. As a result, the development of instrumentation has relied on the slow acquisition of empirical knowledge. Recently, clinicians have expressed interest in the possibility of developing a transcutaneous oximeter that operates in the reflection mode, rather than in the transmission mode. Such a device could be used at many sites on the body, and may enable monitoring during shock and other conditions during which peripheral blood flow is compromised. Our efforts have been focused on improving the theoretical understanding of pulse oximetry. We have developed photon-diffusion models of the skin to study the effect of tissue blood volume and other important variables on the calibration of transmission - and reflection-mode oximeters. Measurements on tissue phantoms and intact skin have been made to confirm the validity of the models. Guided by the model results, we have constructed solid-state reflectance sensors which can be placed on the forehead, face, and chest to obtain measurements of arterial oxygen saturation.