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STEROID DIABETES--METABOLIC PATTERNS AND BASIS FOR TREATMENT

STEROID DIABETES--METABOLIC PATTERNS AND BASIS FOR TREATMENT
类固醇糖尿病——代谢模式和治疗基础
批准号：
3786526
负责人：
MATTHEW C RIDDLE
金额：
$0.0万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3786526
关键词：
carbohydrate metabolism diabetes mellitus therapy drug related diabetes mellitus glucocorticoids hormone regulation /control mechanism human subject noninsulin dependent diabetes mellitus

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中文摘要
翻译
由于器官移植，激素性糖尿病更为普遍。 目前的做法是治疗类固醇糖尿病患者 自发性II型糖尿病，我们认为这是错误的。时间 糖皮质激素的作用过程没有在这方面考虑。 配方。我们将检验这一假设：类固醇糖尿病有一个 不同于自发性的代谢燃料模式 II型糖尿病，与其作用时间进程有关 糖皮质激素对碳水化合物代谢的影响。
英文摘要
Steroid induced diabetes is more prevalent due to organ transplantation. Current practice is to treat persons with steroid diabetes like spontaneous Type II Diabetes, which we feel is incorrect. The time course of action of the glucocorticoid has not been considered in this formulation. We will test the hypothesis: Steroid diabetes had a metabolic fuel pattern distinct and separate from that of spontaneous Type II Diabetes Mellitus, related to the time course of action of glucocorticoids on carbohydrate metabolism.
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