Cytokine Signalling in Health and Disease

健康和疾病中的细胞因子信号传导

• 批准号: nhmrc : GNT1121755
• 负责人: Dr Jeffrey Babon
• 金额: $ 69.76万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cytokine-signalling-health-disease/1347224
• 关键词: Cytokine; Signalling; Health; Disease

The blood system is made up of different types of blood cells (red cells, white cells, platelets etc). The correct number of each type of cell is controlled by chemical messengers called cytokines. Because overactive cytokine signalling can lead to inflammatory disease and leukemia it is tightly controlled by the other molecules in the body. This project aims to determine the exact mechanism whereby this is achieved with the aim of developing therapies to treat inflammatory disease and leukemia.

血液系统由不同类型的血细胞（红细胞、白细胞、血小板等）组成。每种细胞的正确数量是由一种叫做细胞因子的化学信使控制的。因为过度活跃的细胞因子信号传导会导致炎症性疾病和白血病，它受到体内其他分子的严格控制。该项目旨在确定实现这一目标的确切机制，以开发治疗炎症性疾病和白血病的疗法。