MANAGEMENT OF MALIGNANT VENTRICULAR ARRHYTHMIA IN PATIENTS WITH IHSS

IHSS 患者恶性室性心律失常的治疗

• 批准号: 3837966
• 负责人: L FANANAPAZIR
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3837966
• 关键词: arrhythmia; disease /disorder proneness /risk; heart circulation; heart electrical activity; heart pharmacology; human subject; norepinephrine; sudden cardiac death

The purpose of this study is to investigate the effects of reversible left stellate ganglion blockade on cardiac electrical activity, myocardial blood flow and norepinephrine kinetics in a selected group of symptomatic patients with hypertrophic cardiomyopathy (IHSS) who are shown to have inducible malignant ventricular arrhythmias during electrophysiologic studies and who are at high risk of sudden cardiac death. Presently we are awaiting the first patient.

本研究的目的是探讨可逆性左心室肥厚的影响， 星状神经节阻滞对心脏电活动、心肌血液的影响 选定一组有症状的患者的血流和去甲肾上腺素动力学 患有肥厚型心肌病（IHSS）的患者， 电生理过程中诱发恶性室性心律失常 研究和心脏性猝死的高风险人群。 目前， 等待第一个病人。