MANAGEMENT OF MALIGNANT VENTRICULAR ARRHYTHMIA IN PATIENTS WITH IHSS

IHSS 患者恶性室性心律失常的治疗

• 批准号: 3916506
• 负责人: L FANANAPAZIR
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3916506
• 关键词: arrhythmia; drug metabolism; heart block; heart electrical activity; heart pharmacology; heart ventricle; human subject; hypertrophic myocardiopathy; norepinephrine; sudden cardiac death

The purpose of this study is to investigate the effects of reversible left stellate ganglion block on cardiac electrical stability, myocardial blood flow and norepinephrine kinetics in a selected group of symptomatic patients with hypertrophic cardiomyopathy (IHSS) who are shown to have inducible malignant ventricular arrhythmias during electrophysiologic studies and who are at high risk of sudden cardiac death. Presently we are awaiting the first patient.

本研究的目的是调查 可逆性左星状神经节阻滞 稳定性、心肌血流量和去甲肾上腺素动力学 选择一组有症状的肥大性 心肌病（IHSS），被证明具有可诱导的恶性 电生理研究中的室性心律失常， 心脏猝死的风险很高 目前， 等待第一个病人。