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CLINICAL AND EXPERIMENTAL STUDIES OF HEPATITIS B VACCINES

CLINICAL AND EXPERIMENTAL STUDIES OF HEPATITIS B VACCINES
乙型肝炎疫苗的临床和实验研究
批准号：
3822033
负责人：
R H PURCELL
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3822033
关键词：
Asia communicable disease control genetic recombination hepatitis B antigens hepatitis B virus group hepatitis vaccine human subject human therapy evaluation immunogenetics immunological substance infant human (0-1 year) synthetic antigens synthetic peptide synthetic vaccines virus antigen

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中文摘要
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英文摘要
Clinical testing and characterization of one lot of plasma-derived hepatitis B vaccine prepared by the NIAID have been completed. The vaccine was highly immunogenic, safe and well tolerated when tested in healthy persons ranging from infants to adults. Results from an efficacy trial in Asia indicate that the vaccine effectively prevents transmission of hepatitis B virus infection from mothers to infants. The sera from these infants are being analyzed from responses to specific HBsAg epitopes in an attempt to identify those that are most important.
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STUDIES OF ACQUIRED IMMUNE DEFICIENCY SYNDROME
SECOND AND THIRD-GENERATION HEPATITIS B VACCINES
WOODCHUCK HEPATITIS VIRUS
SECOND AND THIRD-GENERATION HEPATITIS B VACCINES
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