Deciphering the role of Scribble in Development and Disease
Deciphering the role of Scribble in Development and Disease
批准号:
nhmrc : GNT1103871
负责人:
A/Pr Helena Richardson
金额:
$62.88万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
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英文摘要
Scribble is a protein that controls the orientation and organization of all cells within our body. Mutations in the Scribble gene are found in many cancers and also in some patients with spina bifida, however how these mutations cause these diseases is not understood. Here we propose experiments that can be used to link Scribble mutations to specific cellular functions. This information will help us design new therapies to treat diseases driven by tissue disorganization such as cancer.
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Deciphering the role of Scribble in Development and Disease
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批准号:nhmrc : 1103871
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项目类别:Project Grants
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资助金额:$43.02万
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财政年份:2016
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负责人:A/Pr Helena Richardson
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依托单位:
Research Fellowship
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批准号:nhmrc : 1020056
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项目类别:Research Fellowships
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资助金额:$45.06万
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财政年份:2012
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负责人:A/Pr Helena Richardson
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依托单位:
Identification of novel tumour suppressors in Ras-mediated tumourigenesis
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批准号:nhmrc : 1020525
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项目类别:Project Grants
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资助金额:$38.71万
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财政年份:2012
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负责人:A/Pr Helena Richardson
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依托单位:
Control of the Ras/Erk signaling pathway by the Brahma chromatin-remodeling complex
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批准号:nhmrc : 1011320
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项目类别:NHMRC Project Grants
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资助金额:$35.0万
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财政年份:2011
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负责人:A/Pr Helena Richardson
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依托单位:
The mechanism by which apical-basal polarity complexes regulate the Salvador-Warts-Hippo pathway
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批准号:nhmrc : 628401
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项目类别:NHMRC Project Grants
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资助金额:$36.01万
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财政年份:2010
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负责人:A/Pr Helena Richardson
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依托单位:
The tumour suppressor Lgl in the regulation of cell signaling, proliferation and apoptosis
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批准号:nhmrc : 509020
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项目类别:NHMRC Project Grants
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资助金额:$35.67万
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财政年份:2008
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负责人:A/Pr Helena Richardson
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依托单位:
Research Fellowship - Grant ID:454700
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批准号:nhmrc : 454700
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项目类别:NHMRC Research Fellowships
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资助金额:$41.26万
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财政年份:2007
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负责人:A/Pr Helena Richardson
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依托单位:
SPARC and SPARC cluster genes in tumourigenesis.
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批准号:nhmrc : 454557
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项目类别:NHMRC Project Grants
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资助金额:$33.57万
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财政年份:2007
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负责人:A/Pr Helena Richardson
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依托单位:
Characterisation of cooperation between cell polarity regulators and oncogenes in tumourigenesis using Drosophila
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批准号:nhmrc : 400211
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项目类别:NHMRC Project Grants
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资助金额:$20.32万
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财政年份:2006
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负责人:A/Pr Helena Richardson
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依托单位:
Characterization of novel inhibitors of G1-S phase progression in Drosophila
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批准号:nhmrc : 350369
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项目类别:NHMRC Project Grants
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资助金额:$30.41万
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财政年份:2005
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负责人:A/Pr Helena Richardson
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依托单位:
Analysis of the Scrib, Dlg and Lgl tumour suppressors in cell cycle regulation using the Drosophila animal model system
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批准号:nhmrc : 299956
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项目类别:NHMRC Project Grants
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资助金额:$31.77万
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财政年份:2004
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负责人:A/Pr Helena Richardson
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 299842
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项目类别:NHMRC Research Fellowships
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资助金额:$22.48万
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财政年份:2004
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负责人:A/Pr Helena Richardson
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依托单位:
THE ROLE OF A NOVEL NEGATIVE CELL CYCLE REGULATORY PATHWAY DURING ANIMAL DEVELOPMENT
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批准号:nhmrc : 209018
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项目类别:NHMRC Project Grants
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资助金额:$27.14万
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财政年份:2002
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负责人:A/Pr Helena Richardson
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依托单位:
Molecular Regulation of Programmed Cell Death
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批准号:nhmrc : 157920
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项目类别:NHMRC Project Grants
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资助金额:$49.57万
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财政年份:2001
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负责人:A/Pr Helena Richardson
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依托单位:
THE ROLE OF NOVEL TUMOUR SUPPRESSORS DURING DEVELOPMENT
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批准号:nhmrc : 104919
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项目类别:NHMRC Project Grants
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资助金额:$13.39万
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财政年份:2000
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负责人:A/Pr Helena Richardson
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依托单位:
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