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Deciphering the role of Scribble in Development and Disease

Deciphering the role of Scribble in Development and Disease
解读涂鸦在发育和疾病中的作用
批准号:
nhmrc : 1103871
负责人:
A/Pr Helena Richardson
金额:
$43.02万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31

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中文摘要
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英文摘要
Scribble is a protein that controls the orientation and organization of all cells within our body. Mutations in the Scribble gene are found in many cancers and also in some patients with spina bifida, however how these mutations cause these diseases is not understood. Here we propose experiments that can be used to link Scribble mutations to specific cellular functions. This information will help us design new therapies to treat diseases driven by tissue disorganization such as cancer.
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Deciphering the role of Scribble in Development and Disease
  • 批准号:
    nhmrc : GNT1103871
  • 项目类别:
    Project Grants
  • 资助金额:
    $62.88万
  • 财政年份:
    2016
  • 负责人:
    A/Pr Helena Richardson
  • 依托单位:
Research Fellowship
  • 批准号:
    nhmrc : 1020056
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $45.06万
  • 财政年份:
    2012
  • 负责人:
    A/Pr Helena Richardson
  • 依托单位:
Identification of novel tumour suppressors in Ras-mediated tumourigenesis
  • 批准号:
    nhmrc : 1020525
  • 项目类别:
    Project Grants
  • 资助金额:
    $38.71万
  • 财政年份:
    2012
  • 负责人:
    A/Pr Helena Richardson
  • 依托单位:
Control of the Ras/Erk signaling pathway by the Brahma chromatin-remodeling complex
国内基金
海外基金
PfAP2-R介导的PfCRT转录调控在恶性疟原虫对喹啉类药物抗性中的作用及机制研究
Sestrin2抑制内质网应激对早产儿视网膜病变的调控作用及其机制研究
  • 批准号:
    82371070
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    赵培泉
  • 依托单位: