Defining factors that contribute to individual diversity in the diet-health axis

饮食健康轴上有助于个体多样性的定义因素

• 批准号: nhmrc : GNT1086851
• 负责人: A/Pr Graham Neely
• 金额: $ 159.86万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/defining-factors-contribute-health-axis/1345680
• 关键词: Defining; factors; contribute; individual; diversity

There is a complex interplay between nutrition and genetics such that one diet maybe good for some but not for others depending on genetic makeup. Preliminary experiments in flies and mice support this. We found that for some flies, diets high in fat are harmful resulting in short life but certain flies resist the harmful effects of fat and live a longer lives. We propose to unravel the gene-environment interaction and determine which genes might lead to optimal health outcomes on certain diets.

营养和遗传之间存在着复杂的相互作用，因此一种饮食可能对某些人有益，但对其他人则不利，这取决于基因构成。在苍蝇和老鼠身上的初步实验支持这一点。我们发现，对于一些苍蝇来说，高脂肪的饮食是有害的，导致寿命缩短，但某些苍蝇抵抗脂肪的有害影响，寿命更长。我们建议解开基因与环境的相互作用，并确定哪些基因可能导致某些饮食的最佳健康结果。