OCULAR MANIFESTATIONS OF THE ACQUIRED IMMUNE DEFICIENCY SYNDROME

艾滋病患者有发生明显眼部疾病的风险 一些问题，其中一些可能会导致失明。不治疗，CMV 视网膜炎是艾滋病患者失明的主要原因。我们已经看过 抗病毒新药磷甲酸钠的作用并测定其 抑制病毒发展的能力。我们也已经开始 激光辅助治疗的有效性探讨 光凝在防止疾病进展中的作用。 在我们的研究过程中，我们还发现了新的表现形式 已知艾滋病患者的感染性病原体，即HZV视网膜炎。在……里面 与国家癌症研究所儿科分会合作，我们 已经跟踪了大约125名有症状的艾滋病毒儿童以确定 疾病的自然病史，并确定 这些儿童有严重的眼部疾病。

Patients suffering from AIDS are at risk of developing significant ocular problems, some of which can lead to blindness. Left untreated, CMV retinitis is a major cause of blindness in AIDS patients. We have looked at the effect of the new antiviral drug foscarnet and determined its ability to inhibit progression of the virus. We have also started investigating the usefulness of adjunctive therapy with laser photocoagulation in preventing progression of the disease. In the course of our studies, we have also identified new manifestations of known infectious agents in patients with AIDS, namely, HZV retinitis. In conjunction with the Pediatric Branch of the National Cancer Institute, we have been following about 125 children with symptomatic HIV to determine the natural history of the disease and to determine the probability of significant ocular disease in these children.