Defining epigenetic predictors of long-term outcomes of preterm birth

定义早产长期结果的表观遗传预测因子

• 批准号: nhmrc : 1083779
• 负责人: A/Pr Christiane Theda
• 金额: $ 27.3万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/defining-epigenetic-predictors-preterm-birth/518956
• 关键词: Defining; epigenetic; predictors; long; term

On average, those born premature do worse health-wise than those born at term. However, some do worse than others. Our aim is to identify these people at birth to better help doctors and parents to closely monitor their health. For this, we will be “reading the diary of pregnancy” in the molecules added to chromosomes in blood during pregnancy in young adults with will characterised states of health. We will analyse DNA from blood that we will extract from stored heel prick spots.

平均而言，早产儿的健康状况比足月新生儿差。然而，有些人比其他人做得更糟。我们的目标是在出生时识别出这些人，以便更好地帮助医生和父母密切监测他们的健康状况。为此，我们将“阅读怀孕日记”，在年轻成年人怀孕期间血液中染色体中添加的分子将具有明显的健康状态。我们将分析血液中的DNA，我们将从储存的脚跟刺痛点提取。