DOUBLE FOCUSING MASS SPECTROMETER/UPGRADED DATA SYSTEM

双聚焦质谱仪/升级数据系统

• 批准号: 3520985
• 负责人: ROBERT G BERGMAN
• 金额: $ 40万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-06-07 至 1992-06-06
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3520985
• 关键词: biomedical equipment purchase; mass spectrometry

The College of Chemistry at the University of California (Berkeley) is requesting funds for the purchase of a double focussing, medium mass range (3,000 AMU) mass spectrometer with Electron Ionization (EI) and Fast Atom Bombardment (FAB) capabilities. In addition, we are requesting funds to upgrade the data system on one of our existing instruments. This equipment is required in our facility because of the obsolescence of our existing low resolution mass spectrometer which was purchased in 1965 and an outdated data system interfaced to another 9 year old mass spectrometer. This equipment will be used for the analysis of samples submitted by eight faculty members whose biomedical research encompass the following: C-N Bond Formation Using Metal-based Reagents Zinc Absorption in Diabetic Pregnant Women Acyclic Stereoselection in Natural Products Synthesis Synthesis of Catalytic Antibodies Synthesis and Characterization of Oligosaccharides Polynuclear Manganese Complexes Design and Synthesis of Peptide Mimics Novel Routes to Physiologically Active Compounds

加州大学（伯克利）化学学院是 申请资金购买双聚焦，中等质量范围 （3，000 AMU）电子电离（EI）和快原子质谱仪 轰炸（FAB）能力。 此外，我们还要求提供资金， 升级我们现有仪器的数据系统。 本设备 是需要在我们的设施，因为我们现有的低淘汰 分辨率质谱仪，购买于1965年和过时的 数据系统连接到另一个9岁的质谱仪。 这 设备将用于分析八个国家提交的样品， 其生物医学研究包括以下内容的教师： 使用金属基试剂形成C-N键 妊娠期糖尿病妇女锌的吸收 天然产物合成中的无环立体选择 催化抗体的合成 寡糖的合成与表征 多核锰配合物 肽模拟物的设计与合成 获得生理活性化合物的新途径