MOLECULAR AND CELLULAR STUDIES OF THE IMMUNE RESPONSE IN THE LABORATORY RABBIT

实验兔免疫反应的分子和细胞研究

• 批准号: 3901016
• 负责人: H KULAGA
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3901016
• 关键词: HIV infections; Retroviridae disease; cell population study; cellular pathology; communicable disease control; disease /disorder model; human T cell lymphotropic virus type 1; human immunodeficiency virus 1; immunopathology; laboratory rabbit; molecular pathology

The value of the laboratory rabbit as a model for human retroviruses is being established for studying the processes, prevention and treatment of retroviral diseases. Rabbit cells can be infected in vitro with HTLV-1 and HIV-1. Infection of this species has been confirmed in outbred rabbits in vivo. The present study describes molecular and cellular evidence for HTLV-1 and HIV-1 infection in this system.

实验室兔子作为人类逆转录病毒模型的价值是 正在建立的研究过程，预防和治疗 逆转录病毒病 兔细胞可以在体外用HTLV-1感染， HIV-1该种属的感染已在1999年的远系繁殖兔中得到证实。 vivo. 目前的研究描述了分子和细胞证据， HTLV-1和HIV-1感染。