DATA COORDINATING CENTER /NATURAL HISTORY OF AIDS

中国民航总局的总体目标是： (A)提供生物统计学支持，以更好地了解 人类免疫缺陷病毒感染的自然史 (B)进行适当的生物统计分析，以 确定风险因素，并采取适当的干预措施限制 疾病的传播和对 (C)生物统计学有助于描述任何生物或 环境因素将改变地球的自然历史 疾病(例如，限制或加速发病率和 与感染相关的死亡率)。 CAMAC研究的具体目标是： (1)为研究自然界提供生物统计学支持 男同性恋者中HIV感染者的病史 世卫组织分析了人口统计、社会文化和行为 自我报告数据，并通过统计将这些数据与 体检结果、艾滋病毒抗体状况、免疫学 以及血液化学和血液学参数的存在 其他病毒的抗体。 (2)统计估计疾病进展速度。 通过比较实验室检查结果(HLA型、CBC、 SMA-12)、免疫学参数(通过流式细胞术)、物理 检查、神经精神病学评估和机电 结果(EEG、EKG、MRI、CAT、神经传导检查、 放射学发现)与行为事件有关。 (3)统计估计人群血清转阴率。 性同性恋者以及决定这些行为 这可能会改变血清转换率。 (4)对共病毒的性质和程度进行统计估计 性行为活跃的男同性恋者中的感染。

The general objectives of the CAMAC are: (a) To provide the biostatistical support to better understand the nature history of HIV infection (b) To conduct the appropriate biostatistical analyses to determine the risk factors, and appropriate interventions to limit the spread of the disease and to (c) biostatistically help characterize any biologic or environmental factors which will alter the natural history of the disease (e.g., either limit or accelerate the morbidity and mortality associated with infection) in this population. The specific objectives of the CAMAC study are: (1) To provide the biostatistical support to study the natural history of HIV infection among a population of homosexual men who analyzing the demographic, socio-cultural and behavioral self-report data and by statistically correlating this data with physical examination findings, HIV antibody status, immunologic and blood chemistry and hematology parameters and the presence of antibodies to other viruses. (2) To statistically estimate the rate of disease progression of infection by comparing laboratory findings (HLA-type, CBC, SMA-12), immunologic parameters (by flow cytometry), physical examinations, neuropsychiatric evaluations and electromechanical findings (EEG, EKG, MRI, CAT, nerve conduction studies, radiographic findings) with behavioral events. (3) To statistically estimate the rate of seroconversion among sexually homosexual men as well as determine those behaviors which may alter the rate of seroconversion. (4) To statistically estimate the nature and extent of co-virus infections among sexually active homosexual men.