JEOL MODEL JEM-1200EX/DP/DP TEMSCAN ANALYTICAL ELECTRON

这一共享工具赠款的目的是获得资金 购买JEOL JEM 1200 TEMSCAN分析电子 显微镜 这个显微镜将被放置在电子 病毒免疫学系显微镜实验室 西南生物医学研究基金会，目前 包含两个透射电子显微镜：AEI EM6B， 1966年购买，日立HU 11C于 1967. 这些显微镜是唯一可用于 SFBR。 两人都超过20岁，经常无法获得 因为年久失修。 更重要的是， 扫描能力，因此扫描EM技术不是 在基金会可用。 两种仪器的更换部件 变得越来越难以获得。 另外这些 显微镜缺乏操作的便利性、对准的简单性 真空和摄像系统的自动化， 节省大量的操作时间，使JEOL 1200 EX TEMSCAN特别适合多用户的需求 设施。 1200 EX TEMSCAN还具有以下几个重要特性 在旧的显微镜中没有，包括聚焦辅助 在低放大率下使用，共心测角台允许 倾斜的样品，高对比度物镜透镜，和 样本室中的极高真空，以减少 样品污染。 这个电子显微镜 要求更换两台显微镜。 主要用户群包括R.E.博士。兰福德布朗森， P.神田，J.S. 艾伦，H.C.小麦吉尔R.S. Kushwaha，J. Eichberg，G.B.哈伯德，T. M. Butler，R.C. 肯尼迪，R.A.德莱莫斯， J.A. Coalson和G.R.德雷曼 用户组的所有成员 使用或期望使用电子显微镜作为主要工具， NIH资助的研究项目。 的年龄和状况 现有的显微镜导致显著的延迟 这些研究成果的质量。 收购 JEOL 1200EX TEMSCAN将提供一个现代化的，可靠的，高 进行传输和传输所需的分辨率仪器 扫描电子显微镜相关研究的主要用户 团体，并将提供电子显微镜服务，这些 调查人员和SFBR的其他成员。

The purpose of this shared instrumentation grant is to obtain funds for the purchase of a JEOL JEM 1200 TEMSCAN analytical electron microscope. This microscope will be housed within the electron microscope laboratory of the Department of virology and Immunology at Southwest Foundation for Biomedical Research, which currently contains two transmission electron microscopes: an AEI EM6B which was purchased in 1966 and an Hitachi HU 11C which was obtained in 1967. These microscopes are the only ones available for use at SFBR. Both are over 20 years old and are frequently unavailable because of disrepair. More important, neither instrument has scanning capability, therefore scanning EM technology is not available at the Foundation. Replacement part for both instruments are becoming increasingly difficult to obtain. In addition, these microscopes lack the ease of operation, simplicity of alignment procedures, and automation of the vacuum and camera systems which save a significant amount of operator time and make the JEOL 1200 EX TEMSCAN particularly well suited to the needs of a multi-user facility. The 1200 EX TEMSCAN also has several important features not available in the older microscopes, including a focusing aid for use at low magnification, a eucentric goniometer stage to allow tilting of the specimen, a high-contrast objective lens, and an extremely high vacuum in the specimen chamber to reduce contamination of samples. This electron microscope is being requested to physically replace both microscopes. The major users group consists of Drs. R.E. Lanford, D.L. Bronson, P. Kanda, J.S. Allan, H.C. McGill, Jr., R.S. Kushwaha, J. Eichberg, G.B. Hubbard, T.M. Butler, R.C. Kennedy, R.A. deLemos, J.A. Coalson, and G.R. Dreesman. All members of the users group use or expect to use electron microscopy as a primary tool in their individual NIH-funded research projects. The age and condition of the existing microscopes cause significant delays and reduced quality of results in these research efforts. The acquisition of a JEOL 1200EX TEMSCAN will provide a modern, reliable, high- resolution instrument needed to carry out both transmission and scanning electron-microscopy-related research of the major users groups and will provide electron microscopy service to these investigators and to other members of SFBR.