GROWTH AND DIFFERENTIATION FACTORS IN BONE AND CARTILAGE

这个项目的目标是调查 软骨和骨骼中的分化因子。这项研究 目前正在研究的项目有：1)骨生成素的纯化 来自牛和人骨；2)生长因子对骨的作用 体内分化；3)转化的区隔 4)转化生长因子β在骨组织中的表达。 软骨与骨发育；5)对人和大鼠的影响 牙基质对骨诱导的作用；6)胰岛素样生长的作用 软骨修复中的因子和其他分化因子，以及 7)成骨素等生长因子对软骨细胞的作用 体内去分化软骨细胞。

The objective of this project is to investigate the growth differentiation factors in cartilage and bone. The research projects currently under study are: 1) purification of osteogenins from bovine and human bone; 2) actions of growth factors on bone differentiation in vivo; 3) compartmentation of transforming growth factor beta in bone; 4) expression of TGF beta during cartilage and bone development; 5) influence of human and rat tooth matrix on bone induction; 6) role of insulin-like growth factors and other differentiation factors in cartilage repair, and 7) role of osteogenin and other growth factors on chondrocytes and dedifferentiated chondrocytes in vivo.