ORAL MANIFESTATION OF HIV INFECTION IN U S MILITARY POPULATION

被检测为血清阳性的美国陆军人员 对于人类免疫缺陷病毒(HIV)，将给予医疗 沃尔特里德陆军医疗中心的检查和治疗 (WRAMC)。这些科目还将有机会 参与一项医学研究方案，以研究自然 艾滋病毒感染史，由沃尔特里德军队管理 研究所(WRAIR--见所附议定书)。口述 组件已由美国国立卫生研究院的工作人员开发 牙科研究(NIDR)与美国陆军医疗和 WRAMC和WRAIR的牙科工作人员。 根据现有的WRAIR自然历史议定书，口述 检查仅限于识别伪膜性病变。 念珠菌病(鹅口疮)，毛状白斑，以及 头颈部淋巴结肿大。增加了 口述部分将允许记录流行率和 各种口腔疾病的发生率与 HIV感染和系统性疾病的阶段。风险因素 也将描述与这些条件相关的特征，以及 口腔表现作为早期预测或标记物的作用 疾病的进展将被阐明。最后一点是， 将对唾液中病毒的传播进行调查。

United States Army personnel who have been tested as seropositive for the Human Immunodeficiency Virus (HIV) will be given medical examinations and treatment at Walter Reed Army Medical Center (WRAMC). These subjects will also be given the opportunity to participate in a medical research protocol to study the natural history of HIV infection, administered by the Walter Reed Army Institute of Research (WRAIR - see attached protocol). An oral component has been developed by staff of the National Institute of Dental Research (NIDR) in collaboration with U.S. Army medical and dental staff at WRAMC and WRAIR. Under the existing WRAIR natural history portocol, the oral examination is limited to the identification of pseudomembranous candidiasis (thrush), hairy leukoplakia, and the detection of enlarged lymph nodes in the head and neck region. The addition of the oral component will permit documentation of the prevalence and incidence of the full range of oral conditions in relation to the stage of HIV infection and systemic disease. Risk factors associated with these conditions will also be characterized, and the role of oral manifestations as early predictors or markers of disease progression will be elucidated. Finally, the role of saliva in the transmission of the virus will be investigated.