DICKENS - A randomised controlled trial of DIaCerein to treat KneE osteoarthritis with effusioN-Synovitis

DICKENS - DIaCerein 治疗膝骨关节炎伴积液滑膜炎的随机对照试验

• 批准号: nhmrc : GNT1147370
• 负责人: Dr Dawn Aitken
• 金额: $ 130.95万
• 依托单位: Antarctic Climate and Ecosystems CRC, University of Tasmania
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/dickens-randomised-controlled-effusion-synovitis/1348817
• 关键词: DICKENS; randomised; controlled; trial; DIaCerein

Knee osteoarthritis (OA) is common, but the current treatments are poor. Almost 60% of people with knee OA have joint inflammation. Patients with inflammation are more likely to experience joint pain and rapid joint destruction. We propose that treating patients with inflammatory knee OA with the anti-inflammatory drug, diacerein, will reduce pain and joint damage.

膝关节骨关节炎（OA）是常见的，但目前的治疗方法很差。几乎60%的膝关节OA患者患有关节炎。炎症患者更有可能经历关节疼痛和快速关节破坏。我们建议用抗炎药双醋瑞因治疗炎症性膝关节骨性关节炎患者，将减少疼痛和关节损伤。