Using magnetic resonance imaging (MRI) to improve understanding of knee osteoarthritis and develop effective therapeutic treatments

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Osteoarthritis is the most common form of arthritis and is increasing markedly due to an ageing population. This program of research uses magnetic resonance imaging (MRI) to improve our understanding about knee osteoarthritis. It will examine knee structural change over time using unique 10-year follow-up MRI measures from a pre-existing case-control study. This program of research will also examine two randomised controlled trials which aim to evaluate therapeutic treatments for the disease.