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DNA METHYLATION and DEMETHYLATION IMBALANCE in CANCER

DNA METHYLATION and DEMETHYLATION IMBALANCE in CANCER
癌症中的 DNA 甲基化和去甲基化不平衡
批准号:
nhmrc : 1088144
负责人:
Dr Clare Stirzaker
金额:
$42.37万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2017-12-31

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中文摘要
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英文摘要
This study will give us new insights into the role of MBD2 and TET proteins in establishing the epigenome and especially will have a major impact in our understanding of the key steps involved in both de novo DNA methylation and demethylation in cancer. Ultimately these new understandings may provide routes to use MBD2 and/or TET proteins as pharmacological targets in cancer treatment.
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会议论文
A CTCF Code for The 3D Cancer Genome Architecture
  • 批准号:
    nhmrc : 1147974
  • 项目类别:
    Project Grants
  • 资助金额:
    $60.39万
  • 财政年份:
    2018
  • 负责人:
    Dr Clare Stirzaker
  • 依托单位:
A CTCF Code for The 3D Cancer Genome Architecture
  • 批准号:
    nhmrc : GNT1147974
  • 项目类别:
    Project Grants
  • 资助金额:
    $89.32万
  • 财政年份:
    2018
  • 负责人:
    Dr Clare Stirzaker
  • 依托单位:
Dissecting Spatial, Regional and Temporal Aspects of the Cancer Epigenome
  • 批准号:
    nhmrc : 1070418
  • 项目类别:
    Project Grants
  • 资助金额:
    $46.02万
  • 财政年份:
    2014
  • 负责人:
    Dr Clare Stirzaker
  • 依托单位:
Role of epigenetic modifyers MBD2 and TET proteins in DNA methylation and demethylation in cancer
  • 批准号:
    nhmrc : 1029584
  • 项目类别:
    Project Grants
  • 资助金额:
    $48.15万
  • 财政年份:
    2012
  • 负责人:
    Dr Clare Stirzaker
  • 依托单位:
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