RETROVIRAL ACTIVITY IN LYMPHOCYTES OF PATIENTS WITH SCHIZOPHRENIA

精神分裂症可能与病毒感染有关的证据 (或病毒)是间接的。这一证据包括 精神分裂症的现象学(只要它可以被模仿 由某些病毒性脑炎引起)，流行病学因素(包括 在冬末早春出生的患者中占主导地位， 南北梯度和偶尔的病例聚集性)，以及 间接实验室证据(某些神经病理中的神经胶质细胞增多症 研究，脊髓液蛋白异常，以及 细胞介导的免疫)。 人类逆转录病毒HTLVI、HTLVII和HIV的发现， 现在已知也会影响中枢神经系统，一起发展 人类逆转录病毒学新技术的出现，使我们有可能 研究这类病毒在病毒性肺炎病因学中的作用 精神分裂症。 慢性阻塞性肺疾病患者外周血淋巴细胞的培养 精神分裂症被确诊，并进行了逆转录病毒检测- 特异酶逆转录酶。

The evidence that schizophrenia may involve infection by a virus (or viruses) has been indirect. This evidence includes the phenomenology of schizophrenia (insofar as it may be mimicked by some viral encephalitides), epidemiological factors (including a predominance among patients with late winter/early spring births, a north-south gradient, and occasional clustering of cases), and indirect laboratory evidence (gliosis in some neuropathological studies, spinal fluid protein abnormalities, and abnormalities in cell-mediated immunity). The discovery of the human retroviruses, HTLVI, HTLVII and HIV, now also known to affect the CNS, together with the development of new techniques in human retrovirology, made it possible to investigate the role of this class of viruses in the etiology of schizophrenia. Cultures of peripheral lymphocytes of patients with chronic schizophrenia were established and tested for the retrovirus- specific enzyme reverse transcriptase.