CHARACTERIZATION OF SPIPERONE BINDING TO HUMAN PERIPHERAL BLOOD LYMPHOCYTES

Spiperone 与人外周血淋巴细胞结合的表征

• 批准号: 3922043
• 负责人: A FEENSTRA
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3922043
• 关键词: binding proteins; central nervous system; chemical binding; dopamine receptor; human tissue; lymphocyte; platelets

Peripheral blood lymphocytes and platelets have been used as model systems for some aspects of the central nervous system. It has been demonstrated that lymphocytes express specific binding sites for neuropeptides. Also, the existence of specific spiperone binding sites was described on these cells. Studies are being conducted to characterize the spiperone binding to human peripheral lymphocytes and related cell lines.

外周血淋巴细胞和血小板已被用作模型 中枢神经系统的某些方面。 它有 淋巴细胞表达特异性结合位点 神经肽 此外，特定螺哌隆的存在 在这些细胞上描述了结合位点。 研究正在 用于表征螺哌隆与人 外周淋巴细胞和相关细胞系。