BOSTON UNIVERSITY APHASIA RESEARCH CENTER

波士顿大学失语症研究中心

• 批准号: 3099254
• 负责人: HAROLD GOODGLASS
• 金额: $ 69.94万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-12-01 至 1990-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3099254
• 关键词: aphasia; chronic brain damage; human subject; language disorders; neuropsychology; psychobiology; psycholinguistics

Analysis of patterns of apraxia and their relationship to lesion site and form of aphasia will be completed on 135 patients. A series of studies based on scans of aphasic patients will examine the relation of lesion to particular aphasia patterns and recovery from aphasia, as well as to brain asymmetry. We will continue to update assessment procedures and to study sex differences in susceptibility to aphasia language functions in aging and dementing subjects will also continue. Studies of syntax will continue with several investigations of receptive processing by agrammatic aphasics in which their output and comprehension profiles are compared as well as their ability to deal on-line with open and closed class vocabulary. Initial data collection will begin with a new cross-modal morphology and syntax battery. In the area of lexical semantics, we plan to initiate a number of concept classification and concept generalization studies. We will continue to collect and analyze data on dissociations among word categories for naming and comprehension. Studies of naming disorders will examine the stability of naming vocabulary in aphasia by test-rates and comparisons. In our examination of written language we will examine the hypothesis that pure word-blindness may be an expression of elevated threshold for all visual percepts. Studies of pragmatics will continue with an examination of right hemisphere damaged patients' appreciation of plausibility and of non-literal implication of messages. Studies of cerebral dominance will emphasize the evaluation of autonamous forms of motor dominance and the biological correlates of non-right handedness.

失用模式及其与病变部位和关系的分析 将对 135 名患者完成失语症测试。 一系列研究 基于失语症患者的扫描，将检查病变与 特定的失语症模式和失语症的恢复以及大脑 不对称。 我们将继续更新评估程序并研究 衰老过程中失语症语言功能易感性的性别差异 疯狂的主题也将继续。 语法研究将继续进行接受性的多项研究 语法失语症患者的处理过程中，他们的输出和理解 比较配置文件以及他们在线处理开放问题的能力 以及封闭式课堂词汇。 初始数据收集将从新的 跨模态形态和语法电池。 在词汇语义领域，我们计划发起一些概念 分类和概念概括研究。 我们将继续 收集和分析用于命名的词类别之间的分离数据 和理解。 命名障碍的研究将检查稳定性 通过测试率和比较来命名失语症词汇。 在我们对书面语言的检验中，我们将检验以下假设： 纯粹的词盲症可能是所有人阈值升高的表现 视觉感知。 语用学研究将通过考试继续进行 右半球受损的患者对合理性的鉴赏能力和 消息的非字面含义。 大脑优势的研究将强调自主能力的评估 运动优势的形式和非正确的生物相关性 惯用手。