APHASIA RESEARCH CENTER

这是临床研究项目的延续， 失语症的神经语言学和神经解剖学方面。从长远来看 目的是促进对正常的机制的理解 语言及其神经基础，从而形成一种连贯的观点 失语症的症状学与特定的脑损伤有关 语言和认知的结构及其修饰语 容量。同时的目标是将发展中的理论见解应用于 以理性为基础的失语症诊断评估和治疗。 拟议项目期内的具体目标和实现方法 它们是： 1.调查句子理解障碍和句子障碍 关于具体认知和认知的解释力的生产 语言学原则。 2.使用以下技巧学习单词产生和单词理解 实时探索这些过程的展开和分解。 3.研究失语症患者的长期康复情况 神经、语言、认知和社会功能。 4.研究失语症患者持久化的基础及其基础 随着治疗的进步。 5.探讨失语症患者语言不流利的神经化学基础。 药物治疗，使用溴隐亭。 6.研究右脑在语言调节中的作用 失语症的康复。 7.研究CT和MRI扫描病变与远期康复的相关性。 特定的语言技能，并比较这两者的效果 成像技术。

This is a continuation of a program for the study of clinical, neurolinguistic and neuroanatomic aspects of aphasia. The long term objectives are to advance the understanding of the mechanisms of normal language and their neural basis so as to develop a coherent view of how the symptomatology of aphasia relates to the injury of particular brain structures and consequent modification of linguistic and cognitive capacities. A concurrent goal is apply developing theoretical insights to a rationally based diagnostic assessment and treatment of aphasia. Specific goals in the proposed project period and methods of accomplishing them are: 1. To investigate disorders of sentence comprehension and sentence production in terms of the explanatory power of specific cognitive and linguistic principles. 2. To study word production and word comprehension with techniques that probe the unfolding of these processes and their breakdown in real time. 3. To study the long term recovery of aphasics in terms of changes in neurological, linguistic, cognitive and social function. 4. To study the basis for perseveration in aphasia, and the basis for its improvement with therapy. 5. To investigate the neurochemical basis of nonfluency in aphasia and its pharmacological treatment, using bromocriptine. 6. To investigate the role of the right hemisphere in mediating language recovery in aphasia. 7. To study the CT and MRI scan lesion correlates of long term recovery in particular language skills and to compare the effectiveness of these two imaging techniques.