Control of inflammation via the phosphorylation of tristetraprolin (TTP)
Control of inflammation via the phosphorylation of tristetraprolin (TTP)
批准号:
G0800207/1
负责人:
Andrew Clark
金额:
$54.81万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2009
资助国家:
英国
项目状态:
已结题
起止时间:
2009 至 --
中文摘要
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英文摘要
Inflammation is normally a short-lived and beneficial response to infection or injury. However, in diseases like rheumatoid arthritis, inflammation persists in the absence of infection or injury, causing pain, disfunction and disfigurement. It is possible that persistent inflammation is due to the failure of resolution mechanisms, which would normally help to terminate an inflammatory response. In this project we are exploring the idea of stimulating or reactivating one of the body s natural inflammatory off-switches in order to treat chronic inflammatory diseases.
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国内基金
海外基金
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