HIGH RESOLUTION MASS SPECTROMETER

高分辨率质谱仪

• 批准号: 3519806
• 负责人: PAUL A BARTLETT
• 金额: $ 30万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-02-23 至 1988-02-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3519806
• 关键词: chemical structure; mass spectrometry

The College of Chemistry at the University of California (Berkeley) is requesting funds for the purchase of a high mass (10,000 amu) high resolution mass spectrometer with Fast Atom Bombardment and Field Desorption capabilities. An instrument of this description is required in our facility because we cannot fulfill our users needs with our present equipment. This instrument will be used for the analysis of samples submitted by nine faculty members whose biomedical research encompasses the following: Synthesis of Peptides and Studies of Enzyme Inhibitors Characterization of Complex Carbohydrates Structural Analysis of Phycobiliproteins Structure and Function of Oligonucleotides Structural Determination and Studies of Protein-Bound Pigments Characterization of Siderophore Complexes Design and Synthesis of Enzyme Catalysts Oligonucleotide Directed Mutagenesis Novel Synthetic Routes of Potentially Physiologically Active Compounds Stereoselective Synthesis of Transition Metal Enolates and Related Organometallic Compounds

加州大学化学学院 （伯克利）正在申请购买高质量的资金 (10 1，000 amu）高分辨率质谱仪 轰击和场解吸附能力。 的工具 我们的设施需要此描述，因为我们不能 用我们现有的设备满足用户的需求。 这 仪器将用于分析由以下机构提交的样品： 九名教职员工，其生物医学研究涵盖 以下内容： 多肽的合成及酶抑制剂的研究 复杂碳水化合物的表征 藻胆蛋白的结构分析 寡核苷酸的结构与功能 蛋白质结合色素的结构测定与研究 铁载体配合物的表征 酶催化剂的设计与合成 寡核苷酸定向诱变 具有潜在生理活性的新的合成路线 化合物 过渡金属烯醇化物的立体选择性合成及 相关有机化合物