课题基金 / 基金详情

SUPPORT FOR REGIONAL PRIMATE RESEARCH CENTER

SUPPORT FOR REGIONAL PRIMATE RESEARCH CENTER
支持区域灵长类研究中心
批准号:
3107901
负责人:
LEONARD LASTER
金额:
$441.44万
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-05-01 至 1989-04-30
关键词:

项目摘要

项目成果

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中文摘要
翻译
该中心的研究计划将继续强调第一次生殖 生物学,然后是心血管和代谢疾病和免疫疾病。 皮肤生物学,已经不再强调,将继续主要对生物学 色素沉着。 生殖生物学研究的重点是 控制排卵,精子发生,生殖器官,受精, 胎盘和胎儿的生理机能 将继续研究 生殖行为的生理基础和特定的生物化学 控制这种行为的代理人。 所有调查将继续进行 跨学科的,并在适当时将利用的贡献 形态学家、生理学家、生物化学家和行为学家。 工作 心血管疾病将寻求更深入的了解生化 控制动脉粥样硬化的机制和调节动脉粥样硬化的因子 胆固醇代谢以及动脉粥样硬化的消退。 工作将 继续控制胆固醇吸收的饮食因素。 将继续对西里伯斯猿类的糖尿病样综合征进行研究。 努力 免疫疾病将集中在过敏反应的生化机制上, 器官移植和癌症免疫疗法。 皮肤生物学的工作将 专注于黑素生成的遗传控制和生物化学基础, 雌性猕猴的性皮肤。
英文摘要
The Center's research program will continue to emphasize first reproductive biology, and then cardiovascular and metabolic diseases and immune diseases. Cutaneous biology, already deemphasized, will continue primarily on the biology of pigmentation. Research in reproductive biology focuses on the events that control ovulation, spermatogenesis, the reproductive organs, fertilization, and the physiology of the placenta and the fetus. Studies will continue on the physiologic basis of reproductive behavior and on the specific biochemical agents that control such behavior. All investigation will continue to be interdisciplinary, and whenever appropriate will engage the contributions of morphologists, physiologists, biochemists, and behaviorists. Work in cardiovascular diseases will pursue deeper understanding of the biochemical mechanisms that control atherosclerosis and the factors that regulate cholesterol metabolism, as well as the regression of atheromata. Work will continue on the dietary factors that control the absorption of cholesterol. Studies will proceed on the diabetes-like syndrome in Celebes apes. Efforts in immune diseases will focus on the biochemical mechanisms of allergic reaction, organ transplantation, and cancer immunotherapy. Work in cutaneous biology will focus on the genetic control and biochemical basis of melanogenesis, and on the sex skin of female macaques.
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PLAN A BIOMEDICAL INFORMATION COMMUNICATIONS CENTER
PLAN A BIOMEDICAL INFORMATION COMMUNICATIONS CENTER
PLAN A BIOMEDICAL INFORMATION COMMUNICATIONS CENTER
PLAN A BIOMEDICAL INFORMATION COMMUNICATIONS CENTER
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