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Developmental Clinical Studies - Gene Therapy For Vein Graft Failure

Developmental Clinical Studies - Gene Therapy For Vein Graft Failure
发育临床研究 - 静脉移植失败的基因治疗
批准号:
G1001147/1
负责人:
Andrew Baker
金额:
$586.5万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2011
资助国家:
英国
项目状态:
未结题
起止时间:
2011 至 --

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中文摘要
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英文摘要
Failure rates for heart bypass grafts using veins remain very high and represent a major clinical problem that lacks a drug-based treatment. Our prior studies have demonstrated the unique ability of gene therapy (the use of a patient s genes to treat the disease) to prevent the vein getting blocked which is associated with graft failure. We wish to perform a clinical trial in patients undergoing bypass grafting and assess the safety and beneficial effect of gene therapy.
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Activation of long non-coding RNA by a gene therapy CRISPR/Cas9 approach to prevent vein graft failure
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    EP/X024563/1
  • 项目类别:
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LADUMA: Reaching the Highest Redshifts with the Deepest HI Survey
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    2308161
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Collaborative Research: Investigating the genomic basis of key performance traits to quantify the evolutionary potential of coral populations under climate change
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    2023155
  • 项目类别:
    Standard Grant
  • 资助金额:
    $18.6万
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Collaborative Research: Assessing the changing symbiotic milieu on Caribbean coral reefs under climate change: magnitude, tradeoffs, interventions, and implications
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    1851392
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  • 财政年份:
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国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data