Development Clinical Studies - investigation into the efficacy of Mirococept in renal transplantation

开发临床研究-Mirococept在肾移植中的疗效调查

• 批准号: G1001197/1
• 负责人: Steven Sacks
• 金额: $ 330.55万
• 依托单位: King's College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2011
• 资助国家: 英国
• 起止时间: 2011 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G1001197%2F1
• 关键词: Development; Clinical; Studies; investigation; into

This study is designed to improve the immediate function of a kidney transplant and also to improve its longterm outcome. A novel molecule has been designed that binds to the cell membranes of the kidney and reduces the inflammatory response after transplantation. This should result in a shorter hospital stay for the patient and a reduced need for dialysis after transplantation. There is also good evidence that improving the initial function of a kidney can improve longterm fuction, thus improving the outcome for the patient. This would also increase the number of kidneys available for transplanation to those on the waiting list.

这项研究旨在改善肾移植的即时功能，并改善其长期结果。一种新的分子已经被设计出来，它可以与肾脏的细胞膜结合，减少移植后的炎症反应。这将缩短患者的住院时间，并减少移植后透析的需要。也有很好的证据表明，改善肾脏的初始功能可以改善长期功能，从而改善患者的预后。这也将增加等待名单上可供移植的肾脏数量。