Development Clinical Studies - investigation into the efficacy of Mirococept in renal transplantation
Development Clinical Studies - investigation into the efficacy of Mirococept in renal transplantation
批准号:
G1001197/1
负责人:
Steven Sacks
金额:
$330.55万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2011
资助国家:
英国
项目状态:
已结题
起止时间:
2011 至 --
中文摘要
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英文摘要
This study is designed to improve the immediate function of a kidney transplant and also to improve its longterm outcome. A novel molecule has been designed that binds to the cell membranes of the kidney and reduces the inflammatory response after transplantation. This should result in a shorter hospital stay for the patient and a reduced need for dialysis after transplantation. There is also good evidence that improving the initial function of a kidney can improve longterm fuction, thus improving the outcome for the patient. This would also increase the number of kidneys available for transplanation to those on the waiting list.
期刊论文(0)
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会议论文
Efficacy of Mirococept (APT070) for Preventing Ischaemia-Reperfusion Injury associated with Kidney Transplantation-2 (EMPIRIKAL-2)
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批准号:MR/V038281/1
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项目类别:Research Grant
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资助金额:$578.86万
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财政年份:2022
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负责人:Steven Sacks
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依托单位:
Measuring the impact of monoclonal antibody drugs in cancer and rheumatoid arthritis
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批准号:MC_PC_20057
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项目类别:Intramural
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资助金额:$13.71万
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财政年份:2021
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负责人:Steven Sacks
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依托单位:
Characterisation of glycan ligands recognised by collectin-11 in ischaemic kidney and development of a specific antagonistic probe
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批准号:MR/R010757/1
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项目类别:Research Grant
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资助金额:$93.99万
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财政年份:2018
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负责人:Steven Sacks
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依托单位:
Collectin-11 as a trigger of the innate immune response in renal transplantation
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批准号:MR/M012263/1
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项目类别:Research Grant
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资助金额:$71.41万
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财政年份:2015
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负责人:Steven Sacks
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依托单位:
MRC Centre for Transplantation
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批准号:MR/J006742/1
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项目类别:Research Grant
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资助金额:$260.2万
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财政年份:2012
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负责人:Steven Sacks
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依托单位:
Emerging diagnostic and treatment approaches in organ and stem cell transplantation
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批准号:G0600698/1
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项目类别:Research Grant
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资助金额:$268.75万
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财政年份:2007
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负责人:Steven Sacks
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依托单位:
Targeting the complement system in transplantation
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批准号:G0600892/1
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项目类别:Research Grant
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资助金额:$163.07万
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财政年份:2007
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负责人:Steven Sacks
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依托单位:
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
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批准号:31070748
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项目类别:面上项目
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资助金额:34.0万元
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批准年份:2010
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负责人:Christine Nardini
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依托单位: