Detection of Cardiac Allograft Rejection by Peripheral Blood Gene Expression: A Novel Concept of Personalized Approach to Transplantation.

点击翻译按钮获取中文摘要

Heart biopsy is required to detect rejection after heart transplantation. The cost of each biopsy is around $7,000 and at least 10 heart biopsies needed in the first post-transplant year alone. The biopsy is difficult for the patients and significant cost for the Australian healthcare system. Thus, it would be beneficial to identify rejection using a simple blood test. Such tool would help to reduce or eliminate the need for expensive heart biopsy and would reduce the cost by about 10 times.