CASE-CONTROL STUDIES OF SELECTED CANCER SITES

选定癌症部位的病例对照研究

• 批准号: 4692281
• 负责人: R N HOOVER
• 金额: --
• 依托单位: DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4692281
• 关键词: antihypertensive agents; bladder neoplasm; breast neoplasm /cancer diagnosis; breast neoplasms; cancer information system; cancer risk; case history; chemical related neoplasm /cancer; child (0-11); coffee; congenital disorders; drug related neoplasm /cancer; embryo /fetus toxicology; environment related neoplasm /cancer; environmental toxicology; estrogens; eye neoplasms; female antifertility drug; human population study; human subject; interview; lifestyle; lymphoma; mesothelioma; multiple myeloma; mycosis; mycosis fungoides lymphoma; neoplasm /cancer diagnosis; neoplasm /cancer education; neoplasm /cancer epidemiology; nose neoplasm; nutrition aspect of cancer; nutrition related tag; occupational disease /disorder; ovary neoplasms; pediatric neoplasm /cancer; psychophysiology; questionnaires; rectum neoplasms; skin neoplasms; statistics /biometry; sweetening agents; testis neoplasms; tranquilizer; water pollution

The purpose of this project is to investigate, in analytic studies, the etiologies of selected cancers. Specific cancer sites and hypotheses are selected for which the need for investigation is clear but which have been difficult to study elsewhere. Case-control studies either recently completed or in progress include studies of the following sites or types: breast cancer, childhood and adult bladder cancer, colorectal cancer, cutaneous T-cell lymphomas, non-Hodgkin's lymphoma, leukemia, multiple myeloma, nasal cancer, testicular cancer, mesothelioma, intraocular melanoma, ovarian cancer, cervical cancer and choriocarcinoma. The studies focus either on tumors that have not been studied analytically before (e.g., because of the rarity of the tumor) or on hypotheses that are difficult to assess (e.g., because of the prevalence of the exposure or the need to detect an effect at low levels of exposrue). Since these studies are often the first or most thorough to date, they collect data on a wide range of exposures, usually from interviews and medical records.

这个项目的目的是在分析研究中调查 选定癌症的病因。具体的癌症部位和假设是 被选中的人显然需要调查，但已经 在其他地方很难研究。最近的病例对照研究 已完成或正在进行的研究包括以下地点或类型的研究： 乳腺癌，儿童和成人膀胱癌，结直肠癌， 皮肤T细胞淋巴瘤，非霍奇金淋巴瘤，白血病，多发性 骨髓瘤、鼻癌、睾丸癌、间皮瘤、眼内 黑色素瘤、卵巢癌、宫颈癌和绒毛膜癌。这些研究 把重点放在以前没有分析过的肿瘤上 (例如，由于肿瘤的罕见)或基于以下假设 难以评估(例如，由于暴露的普遍性或 需要在低暴露水平下检测效果)。因为这些研究 通常是迄今为止第一个或最彻底的，他们收集广泛的数据 暴露的范围，通常来自面谈和医疗记录。