VISUAL INATTENTION AFTER POSTERIOR CEREBRAL HEMISPHERE LESIONS

大脑后半球损伤后的视觉注意力不集中

• 批准号: 4693356
• 负责人: J N CURRIE
• 金额: --
• 依托单位: NATIONAL EYE INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4693356
• 关键词: Alzheimer's disease; brain injury; brain neoplasms; human subject; reading disorder; schizophrenia; visual tracking

A sub group of dyslexic patients with square wave jerks present during fixation and reading was identified and both reading ability and square wave intrusions were markedly improved with methylphenidate. Directionally cued visual behavior is impaired in the visual field contralateral to parietal lesions in humans, but diffusely cued visual tasks are impaired in both visual fields. Similar deficits are found when lesions are made in area 7 or the lateral pulvinar of the macaque. Pursuit function was studied in patients with parietal and frontal lobe lesions, schizophrenia and Alzheimer's disease, and a comparison was made with slow phase velocity of OKN. The frequency of fixational square wave jerks was also studied in the above patients and also in patients with hypothalamic and chiasmal tumors. Cortical visual loss occurred as a temporary side effect in four patients receiving high dose intravenous chemotherapy for lymphoma or leukemia. Magnetic resonance scanning showed good anatomic correlation, with occipital lobe edema. Positron emission scanning (PET) was used to correlate visual functions with glucose utilization in different anatomical areas of the brain. This included patients with homonymous hemianopias, bilateral optic nerve transection and albinism. The possible contribution of extrageniculostriate pathways to visual processing following lesions of the geniculostraite pathway was studied in patients with lesions of optic chiasm, primary visual cortex or optic radiations.

一个亚组的睡眠障碍患者方波抽搐出现在 固定和阅读能力被确定，阅读能力和平方 哌醋甲酯明显改善了波侵入。 方向线索视觉行为在视野中受损 对侧顶叶病变在人类，但弥漫性提示视觉 在两个视野中的任务都受损。 类似的缺陷被发现时， 在猕猴的第7区或外侧枕中产生损伤。 追求 研究了顶叶和额叶病变患者的功能， 精神分裂症和阿尔茨海默病，并与缓慢的 OKN的相速度 注视方波抽搐的频率为 也在上述患者和下丘脑患者中进行了研究 和视交叉肿瘤 四名患者出现暂时性皮质视力丧失的副作用 接受大剂量静脉化疗治疗淋巴瘤或白血病。 磁共振扫描显示解剖相关性良好， 枕叶水肿 正电子发射扫描（PET）被用来关联视觉功能 大脑不同解剖区域的葡萄糖利用率。 这 包括双侧视神经偏盲患者， 横切和白化病。 膝状体纹状体外神经通路对视觉功能的可能作用 在膝状肌层通路损伤后的处理进行了研究， 视交叉、初级视皮层或视神经损伤的患者 辐射