CORONARY VASCULAR TONE AFTER CORONARY BYPASS OPERATIONS

这项临床研究验证了冠状动脉血流动力学 的患者可能会在即刻间隔内发生改变;冠状动脉造影后， 动脉旁路手术可能对患者的未来有害 当然，如果不承认。 6例患者接受了完整的研究。 热 将稀释导管放置在冠状窦中并穿入 大前静脉 端口位于头端和更近端，用于混合 废水取样 血液样本用于测定局部氧含量 消耗，酸碱平衡，乳酸，丙酮酸，肌酸激酶和 乳酸脱氢酶同工酶浓度。 竞争血流动力学 在手术后以连续的方式进行评价6-8小时。 迄今为止的结果表明，对血流的反应变化很大 增强 在某些情况下，冠状动脉血管无显著变化 阻力、心输出量或任何生化变量发生。 其他患者显示的变化可能与不太理想的 收缩性和体循环流量。

This clinical study tests the hypothesis that coronary blood flow dynamics of patients may be altered in the immediate interval; after a coronary artery bypass procedure which may be deleterious to the patient's future course if unrecognized. Six patients have had complete studies. A thermal dilution catheter is placed into the coronary sinus and threaded to the great anterios vein. Ports are at the tip and more proximal for mixed effluent sampling. Blood samples are used to determine regional oxygen consumption, acid base balance, lactic acid, pyruvate, creatine kinase and lactic dehydrogenase iso-enzyme concentrations. Compete hemodynamic evaluations are performed in serial fashion for 6-8 hours after operation. The results to date show wide variation of response to blood flow augmentation. In some, no significant changes in coronary vascular resistance, cardiac output, or any of the biochemical variables occur. Other patients show changes which can be related to less than optimal contractility and systemic flow.