COVID-19 Immunity - National Core Study (IMM-NCS)

COVID-19 免疫力 - 国家核心研究 (IMM-NCS)

• 批准号: MC_PC_20031
• 负责人: Paul Moss
• 金额: $ 917.42万
• 依托单位: University of Birmingham
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_20031
• 关键词: COVID; 19; Immunity; National; Core

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity

• DOI: 10.1016/j.celrep.2023.112827
• 发表时间: 2023-07
• 期刊: Cell Reports
• 影响因子: 8.8
• 作者: Yuan Chen;Georgina H Mason;D. O. Scourfield;Alexander Greenshields-Watson;T. Haigh;A. Sewell;H. Long;A. Gallimore;P. Rizkallah;B. MacLachlan;A. Godkin

The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?

• DOI: 10.1038/s41577-021-00631-x
• 发表时间: 2021-12
• 期刊: Nature reviews. Immunology
• 作者: Boyton RJ;Altmann DM
• 通讯作者: Altmann DM

Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia.

• DOI: 10.1136/bmjopen-2023-077946
• 发表时间: 2023-09-28
• 期刊: BMJ OPEN
• 影响因子: 2.9
• 作者: Barber, Vicki S.;Peckham, Nicholas;Duley, Lelia;Francis, Anne;Abhishek, Abhishek;Moss, Paul;Cook, Jonathan A.;Parry, Helen M.
• 通讯作者: Parry, Helen M.

Association of Spike-Specific T Cells With Relative Protection From Subsequent SARS-CoV-2 Omicron Infection in Young Children.

• DOI: 10.1001/jamapediatrics.2022.3868
• 发表时间: 2023-01-01
• 期刊: JAMA pediatrics
• 影响因子: 26.1
• 作者: Dowell AC;Ireland G;Zuo J;Moss P;Ladhani S;sKIDs Investigation Team
• 通讯作者: sKIDs Investigation Team

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study.

• DOI: 10.1016/s2468-1253(22)00005-x
• 发表时间: 2022-04
• 期刊: The lancet. Gastroenterology & hepatology
• 作者: Alexander JL;Kennedy NA;Ibraheim H;Anandabaskaran S;Saifuddin A;Castro Seoane R;Liu Z;Nice R;Bewshea C;D'Mello A;Constable L;Jones GR;Balarajah S;Fiorentino F;Sebastian S;Irving PM;Hicks LC;Williams HRT;Kent AJ;Linger R;Parkes M;Kok K;Patel KV;Teare JP;Altmann DM;Boyton RJ;Goodhand JR;Hart AL;Lees CW;Ahmad T;Powell N;VIP study investigators
• 通讯作者: VIP study investigators