COVID-19 免疫第一阶段 - 国家核心研究-猫眼课题宝

COVID-19 免疫第一阶段 - 国家核心研究

批准号：

MC_PC_20060

负责人：

Paul Moss

金额：

$999.65万

依托单位：

University of Birmingham

依托单位国家：

英国

项目类别：

Intramural

财政年份：

2021

资助国家：

英国

项目状态：

已结题

起止时间：

2021 至 --

来源：

https://gtr.ukri.org/projects?ref=MC_PC_20060

关键词：

Phase COVID 19 Immunity National

项目摘要

项目成果

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中文摘要

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英文摘要

The magnitude and quality of a person's immune response remains a central determinant of clinical outcome following SARS-CoV-2 infection and vaccines now provide an approach for pandemic control. The NCSi programme is designed to co-ordinate and build on UK investments in understanding COVID-19 immunity. These are based around four themes which seek to predict and manage individual risk, protect against acute infection and late effects of infection, prevent primary infection or re-infection, and prepare for future pandemic challenges.

期刊论文(10)

专著(0)

科研奖励(0)

会议论文

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study.

DOI： 10.1016/s2468-1253(22)00005-x

发表时间： 2022-04

期刊：

The lancet. Gastroenterology & hepatology

影响因子： --

作者：

[Alexander JL, Kennedy NA, Ibraheim H, Anandabaskaran S, Saifuddin A, Castro Seoane R, Liu Z, Nice R, Bewshea C, D'Mello A, Constable L, Jones GR, Balarajah S, Fiorentino F, Sebastian S, Irving PM, Hicks LC, Williams HRT, Kent AJ, Linger R, Parkes M, Kok K, Patel KV, Teare JP, Altmann DM, Boyton RJ, Goodhand JR, Hart AL, Lees CW, Ahmad T, Powell N, VIP study investigators]

通讯作者： VIP study investigators

HLA-DR polymorphism in SARS-CoV-2 infection and susceptibility to symptomatic COVID-19.

DOI： 10.1111/imm.13450

发表时间： 2022-05

期刊：

Immunology

影响因子： 6.4

作者：

[]

通讯作者：

Risk of severe COVID-19 outcomes after autumn 2022 COVID-19 booster vaccinations: a pooled analysis of national prospective cohort studies involving 7.4 million adults in England, Northern Ireland, Scotland and Wales.

DOI： 10.1016/j.lanepe.2023.100816

发表时间： 2024-02

期刊：

LANCET REGIONAL HEALTH-EUROPE

影响因子： 20.9

作者：

[Bedston, Stuart, Almaghrabi, Fatima, Patterson, Lynsey, Agrawal, Utkarsh, Woolford, Lana, Anand, Sneha N, Joy, Mark, Crawford, Anna, Goudie, Rosalind, Byford, Rachel, Abbasizanjani, Hoda, Smith, Deb, Laidlaw, Lynn, Akbari, Ashley, Sullivan, Christopher, Bradley, Declan T, Lyons, Ronan A, de Lusignan, Simon, Hobbs, F D Richard, Robertson, Chris, Sheikh, Sir Aziz, Shi, Ting]

通讯作者： Shi, Ting

COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective, case-control study.

DOI： 10.1016/s2468-1253(22)00274-6

发表时间： 2022-11

期刊：

LANCET GASTROENTEROLOGY & HEPATOLOGY

影响因子： 35.7

作者：

[Alexander, James L., Liu, Zhigang, Sandoval, Diana Munoz, Reynolds, Catherine, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Seoane, Rocio Castro, Anand, Nikhil, Nice, Rachel, Bewshea, Claire, D'Mello, Andrea, Constable, Laura, Jones, Gareth R., Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M., Hicks, Lucy C., Williams, Horace R. T., Kent, Alexandra J., Linger, Rachel, Parkes, Miles, Kok, Klaartje, Patel, Kamal V., Teare, Julian P., Altmann, Daniel M., Goodhand, James R., Hart, Ailsa L., Lees, Charlie W., Boyton, Rosemary J., Kennedy, Nicholas A., Ahmad, Tariq, Powell, Nick]

通讯作者： Powell, Nick

Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN study.

DOI： 10.1016/j.jinf.2022.09.004

发表时间： 2022-11

期刊：

JOURNAL OF INFECTION

影响因子： 28.2

作者：

[Atti, Ana, Insalata, Ferdinando, Carr, Edward J., Otter, Ashley D., Castillo-Olivares, Javier, Wu, Mary, Harvey, Ruth, Howell, Michael, Chan, Andrew, Lyall, Jonathan, Temperton, Nigel, Cantoni, Diego, da Costa, Kelly, Nadesalingam, Angalee, Taylor-Kerr, Andrew, Hettiarachchi, Nipunadi, Tranquillini, Caio, Hewson, Jacqueline, Cole, Michelle J., Foulkes, Sarah, Munro, Katie, Monk, Edward J. M., Milligan, Iain D., Linley, Ezra, Chand, Meera A., Brown, Colin S., Islam, Jasmin, Semper, Amanda, Charlett, Andre, Heeney, Jonathan L., Beale, Rupert, Zambon, Maria, Hopkins, Susan, Brooks, Tim, Hall, Victoria]

通讯作者： Hall, Victoria