Determing whether breast stem cells mediate the risk of developing breast cancer

确定乳腺干细胞是否介导患乳腺癌的风险

• 批准号: nhmrc : 1044661
• 负责人: Dr Kara Britt
• 金额: $ 28.93万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/determing-breast-stem-breast-cancer/111678
• 关键词: Determing; whether; breast; stem; cells

Whilst the outcomes for women with breast cancer have improved significantly, the incidence of breast cancer continues to increase. Research needs to focus on prevention now to try to stop the increase. Apart from age, our reproductive behaviour is the largest risk factor for breast cancer. If a woman does not bear children, or has them after 35 years of age, she is at 25-50% increased risk of breast cancer. We would like to determine whether the breast stem cells play a role in this and why.

虽然女性乳腺癌患者的预后有了显著改善，但乳腺癌的发病率仍在继续增加。现在研究需要集中在预防上，以试图阻止这种增长。除了年龄之外，我们的生殖行为是乳腺癌的最大风险因素。如果一个女人不生孩子，或者在35岁以后生孩子，她患乳腺癌的风险增加25-50%。我们想确定乳腺干细胞是否在其中发挥作用以及为什么。