DATA ANALYSIS FROM THE VAGINAL INFECTIONS AND PREMATURITY STUDY

阴道感染与早产(VIP)研究，由 NICHD和NIAID是一项前瞻性研究，旨在调查 生殖道定植与不同性别的关系 微生物与随后早产的发展。它还 结合红霉素预防早产的临床试验 在患有解脲支原体、沙眼衣原体、 和B群链球菌。此外，VIP还收集了大量 关于可能与怀孕有关的各种因素的补充数据 结果。本项目将对这些因素进行分析。已进行的分析 到目前为止，阴道革兰氏染色的预测价值在 B群链球菌的鉴定、描述性流行病学 B群链球菌携带者与已报道的 体力活动与早产的关系 红霉素对B群移居妇女妊娠结局的影响 链球菌与性交之间的关系 不同生殖器官移居者妊娠与早产的关系 微生物。正在分析的问题包括B组的影响 链球菌定植对妊娠结局的影响 细菌性阴道病与妊娠结局及治疗效果 红霉素对定居妇女妊娠结局的影响 沙眼衣原体。

The Vaginal Infections and Prematurity (VIP) Study, jointly sponsored by NICHD and NIAID, is a prospective study designed to investigate the relationship between genital tract colonization with various microorganisms and the subsequent development of preterm birth. It also incorporates a clinical trial of erythromycin to prevent preterm birth among women colonized with Ureaplasma urealyticum, Chlamydia trachomatis, and group B streptococcus. In addition, the VIP collected a wealth of additional data on a variety of factors possibly linked to pregnancy outcome. This project will analyze these factors. Analyses undertaken to date include the predictive value of vaginal Gram stain in the identification of group B streptococcus, the descriptive epidemiology of group B streptococcal carriage, the relationship between reported physical activity and preterm birth, the effect of treatment with erythromycin on pregnancy outcome among women colonized with group B streptococci, and the association between sexual intercourse during pregnancy and preterm birth among colonized with different genital microorganisms. Questions under analysis include the effect of group B streptococcal colonization on pregnancy outcome, the association between bacterial vaginosis and pregnancy outcome, and the effect of treatment with erythromycin on pregnancy outcome among women colonized with Chlamydia trachomatis.