Determining the impact of inherited epigenetic information on development and disease

确定遗传性表观遗传信息对发育和疾病的影响

• 批准号: nhmrc : 1051223
• 负责人: Dr Patrick Western
• 金额: $ 34.12万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/determining-impact-inherited-development-disease/112203
• 关键词: Determining; impact; inherited; epigenetic; information

Recent observations show that the environment in which you live can alter disease susceptibility in your children, without altering the sequence of your genes. This is due to epigenetic mechanisms which control the way the DNA is interpreted. In this study we will study the potential for epigenetic mechanisms to affect sperm production and impact characteristics and disease in the next generation.

最近的观察表明，你生活的环境可以改变你孩子的疾病易感性，而不会改变你的基因序列。这是由于表观遗传机制控制着DNA的解释方式。在这项研究中，我们将研究影响精子产生和影响下一代特征和疾病的表观遗传机制的潜力。