DEVELOPMENT OF AOTF RAMAN SCATTERING MICROSCOPE

AOTF拉曼散射显微镜的研制

• 批准号: 5204130
• 负责人: S GOLDSTEIN
• 金额: --
• 依托单位: NATIONAL CENTER FOR RESEARCH RESOURCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5204130
• 关键词: Raman spectrometry; biomedical equipment development; infrared microscopy; infrared radiation; radiation detector

We are developing a Raman scattering laser scanning microscope. Our novel approach to spectroscopic imaging integrates a commercial optical microscope with a state-of-the-art acousto-optic device (AOTF) and an extremely sensitive low-light-level imaging detector. The instrument is now capable of near-diffraction limited spatial resolution for both Raman and near-infrared (NIR) absorption spectroscopic microscopy, with plans to extend the system into the mid-infrared spectral region.

我们正在开发拉曼散射激光扫描显微镜。 我们的 光谱成像的新方法集成了商业 配备最先进的声光装置 (AOTF) 的光学显微镜 以及极其灵敏的微光成像探测器。 这 仪器现在能够进行近衍射有限空间 拉曼和近红外 (NIR) 吸收分辨率 光谱显微镜，计划将该系统扩展到 中红外光谱区。