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A school-based education programme to reduce salt intake in children and their families

减少儿童及其家庭盐摄入量的学校教育计划

基本信息

批准号：
MR/J015903/1
负责人：
Feng He
金额：
$ 97.08万
依托单位：
Queen Mary University of London
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2012
资助国家：
英国
起止时间：
2012 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=MR%2FJ015903%2F1
关键词：
based education programme reduce salt

项目摘要

Cardiovascular disease (i.e. strokes, heart attacks and heart failure) is the leading cause of death and disability worldwide. Raised blood pressure is a major cause of cardiovascular disease, accounting for 62% of strokes and 49% of heart attacks. Dietary salt intake is the major factor that increases blood pressure and is largely responsible for the rise in blood pressure with age. Although cardiovascular events occur most frequently after the age of 40 years and the prevalence of hypertension is very low in children, the origins of hypertension and cardiovascular disease occur in childhood. Accordingly, the greatest long-term potential to reduce these conditions is to initiate prevention activities in youth. Such a public heath strategy aimed at preventing or slowing the progression of rising blood pressure altogether would have enormous benefits. Previous studies have demonstrated that salt intake plays an important role in regulating blood pressure in children. A lower salt diet in children could prevent the development of hypertension and cardiovascular disease later in life. Despite the evidence above, there is no reliable data on how much salt children are eating now and no strategy on how to keep children on a low salt intake. We propose to carry out a cross-sectional study to determine the current salt intake in children by using the gold standard method, i.e. measuring 24-h urinary sodium. Furthermore, we will carry out a randomised trial to determine whether an education programme targeted at school children can lower salt intake in children and their families. Our study will be carried out in China which is the largest low- and middle-income country in the world. The successful completion of our study will be the start of a national salt reduction programme which will reduce salt intake both in children and in adults. Furthermore, our salt reduction programme could be adopted by many other low- and middle-income countries. A modest reduction in salt intake across the whole population will lower population blood pressure and prevent many thousands of strokes, heart attacks and heart failure each year, and also lead to major cost-savings to individuals, their families and the health services.

心血管疾病(即中风、心脏病发作和心力衰竭)是世界范围内导致死亡和残疾的主要原因。血压升高是心血管疾病的主要原因，占中风和心脏病发作的62%和49%。食盐摄入量是导致血压升高的主要因素，也是血压随年龄增长而升高的主要原因。虽然心血管事件最多发生在40岁以后，儿童高血压患病率很低，但高血压和心血管疾病的起源发生在儿童时期。因此，减少这些情况的最大长期潜力是在青年中开展预防活动。这种旨在完全预防或减缓血压上升进程的公共健康战略将带来巨大的好处。此前的研究表明，盐摄入量在调节儿童血压方面起着重要作用。儿童的低盐饮食可以预防日后的高血压和心血管疾病的发展。尽管有上述证据，但没有可靠的数据表明儿童现在摄入了多少盐，也没有关于如何保持儿童低盐摄入量的策略。我们建议开展一项横断面研究，使用黄金标准方法，即测量24小时尿钠来确定儿童目前的盐摄入量。此外，我们将进行一项随机试验，以确定针对在校儿童的教育计划是否可以降低儿童及其家庭的盐分摄入量。我们的研究将在中国这个世界上最大的中低收入国家进行。我们研究的成功完成将是一项国家减盐计划的开始，该计划将减少儿童和成人的食盐摄入量。此外，我们的减盐方案可以被许多其他低收入和中等收入国家采用。在整个人口中适度减少盐的摄入量将降低人口血压，防止每年数以千计的中风、心脏病发作和心力衰竭，还将为个人、他们的家庭和卫生服务机构节省大量成本。

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

与盐有关的知识，态度和行为及其与中国成年人的24小时尿钠排泄的关系。

DOI：
10.3390/nu14204404
发表时间：
2022-10-20
期刊：
NUTRIENTS
影响因子：
5.9
作者：
Fan, Fang;Li, Yinghua;Li, Li;Nie, Xueqiong;Zhang, Puhong;Li, Yuan;Luo, Rong;Zhang, Gang;Wang, Lanlan;He, Feng J.
通讯作者：
He, Feng J.

Dietary counseling to reduce moderate sodium intake. Concerns about the methods, evidence and feasibility of lowering sodium intake.

DOI：
10.1016/j.eclinm.2023.102053
发表时间：
2023-07
期刊：
ECLINICALMEDICINE
影响因子：
15.1
作者：
Campbell, N. R. C.;Macgregor, G. A.;He, F. J.
通讯作者：
He, F. J.

Restaurant interventions for salt reduction in China: protocol for a randomised controlled trial.

DOI：
10.1136/bmjopen-2020-038744
发表时间：
2020-12-02
期刊：
BMJ open
影响因子：
2.9
作者：
Du W;Zhang J;Li Y;He FJ;Zhou X;Xu Z;Gao Y;Yin L;Chang X;Yan W;Tan M;MacGregor GA;Luo R;Zhang P;Wang H
通讯作者：
Wang H

Comment on Hogas et al. Salt, Not Always a Cardiovascular Enemy? A Mini-Review and Modern Perspective. Medicina 2022, 58, 1175.

DOI：
10.3390/medicina59010051
发表时间：
2022-12-27
期刊：
Medicina (Kaunas, Lithuania)
影响因子：
0
作者：
通讯作者：

2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action.

DOI：
10.1038/s41371-022-00690-0
发表时间：
2023-06
期刊：
JOURNAL OF HUMAN HYPERTENSION
影响因子：
2.7
作者：
Campbell, Norm R. C.;Whelton, Paul K.;Orias, Marcelo;Wainford, Richard D.;Cappuccio, Francesco P.;Ide, Nicole;Neal, Bruce;Cohn, Jennifer;Cobb, Laura K.;Webster, Jacqui;Trieu, Kathy;He, Feng J.;McLean, Rachael M.;Blanco-Metzler, Adriana;Woodward, Mark;Khan, Nadia;Kokubo, Yoshihiro;Nederveen, Leo;Arcand, JoAnne;MacGregor, Graham A.;Owolabi, Mayowa O.;Lisheng, Liu;Parati, Gianfranco;Lackland, Daniel T.;Charchar, Fadi J.;Williams, Bryan;Tomaszewski, Maciej;Romero, Cesar A.;Champagne, Beatriz;L'Abbe, Mary R.;Weber, Michael A.;Schlaich, Markus P.;Fogo, Agnes;Feigin, Valery L.;Akinyemi, Rufus;Inserra, Felipe;Menon, Bindu;Simas, Marcia;Neves, Mario Fritsch;Hristova, Krassimira;Pullen, Carolyn;Pandeya, Sanjay;Ge, Junbo;Jalil, Jorge E.;Wang, Ji-Guang;Wideimsky, Jiri;Kreutz, Reinhold;Wenzel, Ulrich;Stowasser, Michael;Arango, Manuel;Protogerou, Athanasios;Gkaliagkousi, Eugenia;Fuchs, Flavio Danni;Patil, Mansi;Chan, Andy Wai-Kwong;Nemcsik, Janos;Tsuyuki, Ross T.;Narasingan, Sanjeevi Nathamuni;Sarrafzadegan, Nizal;Ramos, Maria Eugenia;Yeo, Natalie;Rakugi, Hiromi;Ramirez, Agustin J.;Alvarez, Guillermo;Berbari, Adel;Kim, Cho-il;Ihm, Sang-Hyun;Chia, Yook-Chin;Unurjargal, Tsolmon;Park, Hye Kyung;Wahab, Kolawole;McGuire, Helen;Dashdorj, Naranjargal J.;Ishaq, Mohammed;Ona, Deborah Ignacia D.;Mercado-Asis, Leilani B.;Prejbisz, Aleksander;Leenaerts, Marianne;Simao, Carla;Pinto, Fernando;Almustafa, Bader Ali;Spaak, Jonas;Farsky, Stefan;Lovic, Dragan;Zhang, Xin-Hua
通讯作者：
Zhang, Xin-Hua