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EFFECT OF PHARMACOLOGIC ORAL GLUCOCORTICOID THERAPY ON PROTEIN METABOLISM

EFFECT OF PHARMACOLOGIC ORAL GLUCOCORTICOID THERAPY ON PROTEIN METABOLISM
药理口服糖皮质激素治疗对蛋白质代谢的影响
批准号：
5218025
负责人：
DAVID J BRILLON
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5218025
关键词：
bioenergetics clinical research glucocorticoids hormone therapy human subject human therapy evaluation hypercortisolism oral administration protein metabolism

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英文摘要
Acute hypercortisolemia is associated with significant alterations in protein metabolism and energy expenditure (EE). In contrast short term administration of synthetic glucocorticoids is not associated with increased EE. This study will directly compare acute and short term glucocorticoid administration to determine if hormonal effect on protein metabolism and energy expenditure dissipated with duration of use.
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