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EFFECT OF GLUCOCORTICOIDS ON ENERGY EXPENDITURE

EFFECT OF GLUCOCORTICOIDS ON ENERGY EXPENDITURE
糖皮质激素对能量消耗的影响
批准号：
6245116
负责人：
DAVID J BRILLON
金额：
$5.36万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-24 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6245116
关键词：
bioenergetics clinical research cortisol glucocorticoids hormone regulation /control mechanism hormone therapy human subject human therapy evaluation hypercortisolism injection /infusion insulin lipolysis

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英文摘要
This study seeks to extend previous observations of increased energy expenditure during long term hypercortisolemia states by addressing the hypothesis that an associated lipolysis is a principal mechanism for this response. Healthy subjects will be evaluated under cortisol associated hyperinsulinemia or euinsulinemia conditions by 2 separate infusion studies of overnight duration. This study will also seek to determine if any residual effect of hypercortisolemia status persists in these subjects.
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EPIDEMIOLOGY OF DIABETES INTERVENTIONS AND COMPLICATIONS (EDIC)
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EPIDEMIOLOGY OF DIABETES INTERVENTIONS AND COMPLICATIONS (EDIC)
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