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PROTEIN METABOLISM IN OBESITY AND NIDDM

PROTEIN METABOLISM IN OBESITY AND NIDDM
肥胖和 NIDDM 中的蛋白质代谢
批准号：
6114013
负责人：
DAVID J BRILLON
金额：
$7.95万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6114013
关键词：
clinical research computer data analysis human data insulin sensitivity /resistance noninsulin dependent diabetes mellitus obesity protein metabolism proteolysis

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英文摘要
Proteolysis is increased in obese diabetic (NIDDM) and nondiabetic individuals compared to nonobese nondiabetics. This study's aim is to determine whether NIDDM is associated with increased proteolysis independent of obesity by evaluating protein kinetics in nonobese diabetic individuals. The investigators will also determine whether NIDDM and obesity are associated with insulin resistance with respect to protein metabolism. Progress report and summary of findings: No patients admitted during this period. Preliminary data showed increased whole body proteolysis in type 2 Diabetes Mellitus, but there were not sufficient subjects for the finding to achieve significance.
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EPIDEMIOLOGY OF DIABETES INTERVENTIONS AND COMPLICATIONS (EDIC)
ACTION TO CONTROL CARDIOVASCULAR RISK IN DIABETES (ACCORD)
ACTION TO CONTROL CARDIOVASCULAR RISK IN DIABETES (ACCORD)
EPIDEMIOLOGY OF DIABETES INTERVENTIONS AND COMPLICATIONS (EDIC)
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