HEPATOCYTES TRANSPLANTATION AND EXTRACORPOREAL LIVER SUPPORT

肝细胞移植和体外肝脏支持

• 批准号: 5220440
• 负责人: ACHILLES DEMETRIOU
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5220440
• 关键词: cell transplantation; clinical research; clinical trials; human subject; human therapy evaluation; liver cells; liver failure

Many patients with liver failure will die while awaiting transplantation. A Bioartificial Liver Assist System (BAL), a device using porcine hepatocytes, has been developed. During the past year the safety of BAL has been established, leading to the design of an FDA-approved, industry supported multicenter clinical trial which will begin in early 1996 to determine the efficacy of BAL in patients awaiting liver transplantation.

许多肝衰竭患者会在等待移植期间死亡。 生物人工肝辅助系统（BAL），一种使用猪的设备 肝细胞，已发育。 过去一年中BAL的安全状况 已经建立，导致了 FDA 批准的工业设计 supported multicenter clinical trial which will begin in early 1996 to 确定 BAL 对等待肝移植的患者的疗效。