Admin. Supp. for NCI P30 Cancer Center Grants to Facilitate the Development of Standardized Electronic Treatment Plan Builds for NCI-Supported Clinical Trials Applicable Across Clinical Research Sites

项目摘要 电子健康记录（EHR）在所有NCI支持的癌症中心使用。EHR数据不仅支持 提供标准治疗，以及临床研究中的诊断和介入项目 research.尽管基于电子健康记录的护理计划为护理过程提供了质量控制， 这些程序从一个医疗保健提供者到另一个医疗保健提供者有很大的不同，即使 两个组织使用相同的EHR。在支持研究药物的临床试验时， 治疗计划通常从非常基本的数据收集表格构建，无论患者是否 人口是罕见的还是常见的。多机构临床试验需要反复修改不同的EHR 系统可能存在于数百个机构中。此应用程序的目标是创建一个 癌症中心联盟将与NCI和EHR供应商进行沟通和协调， 促进和协调EHR研究或介入治疗计划的快速实施 用于NCTN临床试验俄亥俄州州立大学综合癌症中心将参加本次BIG 10- EHRC联盟项目，其中包括印第安纳州大学的协调中心和五个成员 中心，包括：俄亥俄州州立大学，密歇根大学，爱荷华州大学，西北大学， 和罗格斯大学在十大癌症研究联盟。该项目有以下三个 具体目的：1）回顾性分析EHR治疗计划设计的异同， 在十大成员机构中实施; 2）开发新的EHR治疗计划工具包 有利于NCTN临床试验的快速开展; 3）前瞻性验证EHR治疗方案 在十大机构中实施。

PROJECT SUMMARY Electronic health records (EHR) are used in all NCI-supported Cancer Centers. EHR data support not only the delivery of standard-of-care treatments, but also investigational diagnostic and interventional programs in clinical research. Although EHR-based care plans provide quality control for care processes, such as the administration of pharmaceuticals, these procedures vary extensively from one health care provider to another, even when the same EHR is used by both organizations. In supporting clinical trials with investigational agents, the electronic treatment plan is usually constructed from very basic data collection forms, regardless of whether a patient population is rare or common. Multi-institutional clinical trials require repeated efforts to modify different EHR systems present across potentially hundreds of institutions. The goal of this application is to create a consortium of Cancer Centers that will communicate and coordinate with the NCI and EHR vendors to facilitate and harmonize rapid implementation of EHR investigational or interventional treatment plans for NCTN clinical trials. The Ohio State University Comprehensive Cancer Center will participate in this BIG10- EHRC consortium project, which includes a Coordination Center at the Indiana University and five membership centers, including: The Ohio State University, University of Michigan, University of Iowa, Northwestern University, and Rutgers University within the Big 10 Cancer Research Consortium. The project has the following three specific aims: 1) To retrospectively analyze similarities and differences of EHR treatment plan design and implementation across the member institutions in the Big Ten; 2) To develop novel EHR treatment plan tool kits conducive to rapid opening of NCTN clinical trials; and 3) To prospectively validate EHR treatment plan implementation across Big Ten institutions.