EFFECTS OF CHOLECYSTOKININ & ERYTHROMYCIN ON GASTRIC ACTIVITY

恶心和上呼吸道模糊症状的机制 腹部不适仍然未知。 胃电紊乱 节奏与晕动病症状有关，特别是恶心 上腹部不适 胆囊收缩素被认为是一种 “饱腹激素”和严重的饱腹感类似于恶心。 此外，本发明还提供了一种方法， 包括红霉素在内的许多抗生素会引起恶心和上腹部不适， 不适因此，本研究的目的是确定是否 胆囊收缩素和红霉素引起胃电异常 这是在晕车时记录的。肌电活动将 通过使用Ag-AgCl EKG型电极进行记录， 放在上腹部。 这些研究将进一步促进我们的 了解CCK的胃和激素机制， 红霉素引起的恶心。

The mechanisms which underlie the symptoms of nausea and vague upper abdominal discomfort remain unknown. Disturbances in gastric electrical rhythms are associated with motion sickness symptoms especially nausea and vague upper abdominal discomfort. Cholecystokinin is considered a 'satiety hormone' and severe satiety is similar to nausea. In addition, many antibiotics including erythromycin cause nausea and upper abdominal discomfort. Therefore, the purpose of this study is to determine whether cholecystokinin and erythromycin produce gastric electrical abnormalities which are recorded during motion sickness. Myoelectrical activity will be recorded by the use of Ag-AgCl EKG type electrodes which will be placed over the upper abdomen. These studies will further our understanding of the gastric and hormonal mechanism of CCK and erythromycin-induced nausea in humans.