CLINICAL TRIAL: NORIG
CLINICAL TRIAL: NORIG
批准号:
8167044
负责人:
KENNETH L KOCH
金额:
$0.17万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-03-01 至 2011-02-28
关键词:
ClinicalClinical TrialsComputer Retrieval of Information on Scientific Projects DatabaseFDA approvedFundingGastroparesisGrantHypersensitivityInstitutionMental DepressionNortriptylinePatientsProcessResearchResearch PersonnelResourcesSourceSymptomsTherapeutic AgentsTricyclic Antidepressive AgentsUnited States National Institutes of HealthVisceralclinical practiceresponse
中文摘要
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得了主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者所在的机构。
本研究将确定胃轻瘫患者对去甲替林(一种症状调节剂/三环类抗抑郁药)治疗的临床反应。去甲替林被FDA批准用于治疗抑郁症。本研究将评价患者的症状和潜在的病理生理异常是否对去甲替林针对内脏高敏感性/中央处理的反应。虽然这种治疗剂在许多临床实践中用于胃轻瘫,但缺乏证据表明这种治疗对症状性胃轻瘫有效。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This study will determine the clinical responses of patients with gastroparesis to treatment with nortriptyline, a symptom modulator/tricyclic antidepressant. Nortriptyline is FDA approved for treatment of depression. This study will evaluate whether patients= symptoms and underlying pathophysiologic abnormalities respond to nortriptyline directed towards visceral hypersensitivity/central processing. Although this therapeutic agent is employed in many clinical practices for gastroparesis, there is a lack of evidence that this treatment may be effective in symptomatic gastroparesis.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
GASTROPARESIS REGISTRY
-
批准号:8167022
-
项目类别:
-
资助金额:$8.77万
-
财政年份:2010
-
负责人:KENNETH L KOCH
-
依托单位:
GASTROPARESIS REGISTRY
-
批准号:7951394
-
项目类别:
-
资助金额:$7.15万
-
财政年份:2009
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负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis, Gastric Dysrhythmias, and Dyspepsia Symptoms in Type 2 Diabetes
-
批准号:7905304
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项目类别:
-
资助金额:$15.0万
-
财政年份:2009
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis, Gastric Dysrhythmias, and Dyspepsia Symptoms in Type 2 Diabetes
-
批准号:7615734
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项目类别:
-
资助金额:$34.38万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis Consortium Continuation and New Type 2 Diabetes Mellitus Studiies
-
批准号:8545795
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项目类别:
-
资助金额:$30.24万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Subtypes of Gastroparesis
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批准号:9357567
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项目类别:
-
资助金额:$38.75万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis, Gastric Dysrhythmias, and Dyspepsia Symptoms in Type 2 Diabetes
-
批准号:7941525
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项目类别:
-
资助金额:$27.02万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Exploration of Subtypes of Gastroparesis and Gastroparesis-like Symptoms based on Physiological Testing
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批准号:10318464
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项目类别:
-
资助金额:$38.75万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis, Gastric Dysrhythmias, and Dyspepsia Symptoms in Type 2 Diabetes
-
批准号:7430434
-
项目类别:
-
资助金额:$33.21万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis, Gastric Dysrhythmias, and Dyspepsia Symptoms in Type 2 Diabetes
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批准号:7219973
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项目类别:
-
资助金额:$33.47万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis, Gastric Dysrhythmias, and Dyspepsia Symptoms in Type 2 Diabetes
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批准号:7872906
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项目类别:
-
资助金额:$28.6万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis, Gastric Dysrhythmias, Dyspepsia in T2DM
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批准号:7032028
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项目类别:
-
资助金额:$34.83万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Subtypes of Gastroparesis
-
批准号:10001028
-
项目类别:
-
资助金额:$38.75万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis Consortium Continuation and New Type 2 Diabetes Mellitus Studiies
-
批准号:8730126
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项目类别:
-
资助金额:$30.31万
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财政年份:2006
-
负责人:KENNETH L KOCH
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依托单位:
Gastroparesis Gastric Dysrhythmias and Dyspepsia Symp*
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批准号:7497377
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项目类别:
-
资助金额:$0.98万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis Consortium Continuation and New Type 2 Diabetes Mellitus Studiies
-
批准号:8114367
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项目类别:
-
资助金额:$36.19万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
Gastroparesis Consortium Continuation and New Type 2 Diabetes Mellitus Studiies
-
批准号:8327156
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项目类别:
-
资助金额:$30.31万
-
财政年份:2006
-
负责人:KENNETH L KOCH
-
依托单位:
EFFECTS OF CHOLECYSTOKININ & ERYTHROMYCIN ON GASTRIC ACTIVITY
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批准号:5225853
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:KENNETH L KOCH
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依托单位:--
海外基金