PORTABLE STEREO DIGITAL FUNDUS CAMERA

申请公司提议开发便携式数字立体眼底照相机。拟议的照相机将提高质量和经济的筛查和提供护理的视网膜和脉络膜变性疾病。 将对该摄像机进行视网膜脱离、糖尿病视网膜病变、视网膜裂孔、视网膜前膜、视网膜母细胞瘤、眼部肿瘤、早产儿视网膜病变和眼科视神经盘杯的诊断筛查评价。 拟议的研究将导致开发一个预产品原型单位，实现高分辨率数字立体眼底成像的手持设备。 在第二阶段研究期间，将开发一个初始原型相机，并通过对模型眼睛和100名人类患者进行成像进行测试。 本研究的结果将用于确定对相机设计的必要修改。 将实施这些变更，并制造和测试预产品原型。 在第二项临床研究中，来自偏远地区的患者将使用相机进行成像，并将图像传输到加州戴维斯大学医学中心进行评估。 眼科专家将评估该相机在临床环境中的有效性及其在现场临床图像采集和数字传输到非现场位置中的有用性。拟议的商业应用：对于所提出的仪器在糖尿病视网膜病变、黄斑变性和视网膜的其它血管疾病的筛查和治疗中的应用存在大的商业市场。应用包括监狱、疗养院、军事场所和退休社区以及美洲原住民保留地的临床和远程医疗站点。

The applicant firm proposes the development of a portable digital stereo fundus camera. The proposed camera would enhance the quality and economies of screening and providing care for degenerative diseases of the retina and choroid. The camera will be evaluated for diagnostic screening of retinal detachments, diabetic retinopathy, retinal holes, epiretinal membranes, retinalblastomas, ocular tumors, retinopathy of prematurity and glaucomatist optic disc cupping. The proposed research will result in the development of a pre-product prototype unit that achieves high resolution digital stereo fundus imaging in a hand held unit. During the Phase II research an initial prototype camera will be developed and tested by imaging a model eye and one hundred human patients. Results of this study will be used to determine necessary modifications to the camera design. These changes will be implemented and a pre-product prototype will be fabricated and tested. In a second clinical study patients from remote sites will be imaged with the camera and images transmitted to the University of California Davis Medical Center for evaluation. Ophthalmic specialists will evaluate the camera's effectiveness in a clinical setting and its usefulness in the clinical acquisition of images onsite and digital transmission to off site locations. PROPOSED COMMERCIAL APPLICATIONS: A large commercial market exists for application of the proposed instrument in screening and treatment of diabetic retinopathy, macular degeneration, and other vascular diseases of the retina. Applications include clinical and telemedicine sites at prisons, nursing homes, military sites, and retirement communities, and Native American reservations.